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Module 2 Set A (Pharmacy)

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Medicine Quiz on Module 2 Set A (Pharmacy), created by Bryan Suringa on 06/11/2020.
Bryan Suringa
Quiz by Bryan Suringa, updated more than 1 year ago
Bryan Suringa
Created by Bryan Suringa about 4 years ago
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Resource summary

Question 1

Question
What two enzymes are used to bypass the pyruvate kinase reaction of glycolysis? I. pyruvate carboxylase II. PEP carboxykinase (PEPCK) III. Fructose bisphosphatase IV. Glucose-6-phosphate
Answer
  • A. I & II
  • III & IV
  • II & IV
  • II & III

Question 2

Question
Which of the following includes the main goals of Pentose Phosphate Pathway? I. produce ribose-5-phosphate for nucleotide synthesis II. produce NADPH and NADP for oxidoreductive biochemical synthesis III. to interconvert pentoses and hexoses
Answer
  • I & II
  • II & III
  • I & III
  • I, II & III

Question 3

Question
Which of the following statements is/are true regarding the secondary structure of nucleic acids? I. Guanine forms base pairs with cytosine via 2 hydrogen bonds II. The B form of the DNA is the most common in biological systems III. The breaking of H-bonds caused by high temperature is called melting
Answer
  • I,II & III
  • I & II
  • II & III
  • I & III

Question 4

Question
The phospholipid, phosphatidylinositol 4,5-bisphosphate forms the potent secondary messengers inositol triphosphate & diacylglycerol via what enzyme?
Answer
  • Phospholipase A
  • Phospholipase C
  • Phospholipase D
  • Phospholipase B

Question 5

Question
Which of the following is not true regarding the four enzyme complexes of the electron transport chain?
Answer
  • Complex I is known as the NADH-CoQ Oxidoreductases
  • Complex II is known as Succinate-CoQ Oxidoreductases
  • Complex III is known as Cytochrome Oxidase
  • Complex IV is known as Cytochrome Oxidase

Question 6

Question
Glucose and mannose are epimers at:
Answer
  • Carbon 4
  • Carbon 2
  • Carbon 3
  • Carbon 5

Question 7

Question
One important endogenous molecule for synthetic biotransformation of xenobiotics is glucuronic acid. It is actually the most dominant conjugative biotransformation pathway due to the readily available source of glucose. It is produce from glucose via:
Answer
  • Oxidation at carbon 1
  • Oxidation at carbon 2
  • Oxidation at carbon 6
  • Oxidation at carbon 1 & 6

Question 8

Question
Which of the following is not true about protein structure determination?
Answer
  • NMR is the only means of determining protein structure
  • Protein are difficult to crystallize, a disadvantage of x-ray crystallography
  • An advantage of the use of the NMR is that proteins analyzed are in their natural state
  • Large and very complex proteins can only be analyzed by x-ray crystallography

Question 9

Question
Tertiary structures of proteins are primarily stabilized by I. H-bonds II. Hydrophobic interactions III. Ionic bonds IV. Disulfide bonds
Answer
  • I, II, III & IV
  • I, II& IV
  • I,III & IV
  • I & III

Question 10

Question
In an uncompetitive inhibition of enzymatic action :
Answer
  • Inhibitor binds either to the free enzyme or the enzyme substrate complex
  • Lineweaver-Burk plots of the enzyme alone (control) & the enzyme + inhibitor are parallel to each other
  • The apparent Km is raised
  • The Vmax is unaffected

Question 11

Question
Which biomolecule is not considered a biopolymer?
Answer
  • Proteins
  • Lipids
  • Nucleic acids
  • Carbohydrates

Question 12

Question
It is regarded as the universal biological energy currency
Answer
  • Adenosine triphosphate
  • Guanosine triphosphate
  • Uncouplers
  • Calories

Question 13

Question
This is the final electron acceptor of the electron transport chain in aerobic respiration.
Answer
  • Complex I
  • Complex I&II
  • Nitrate
  • Oxygen

Question 14

Question
The most accepted hypothesis regarding oxidative phosphorylation is
Answer
  • Chemical coupling
  • Conformational coupling
  • Chemiosmotic hypothesis
  • Lock and Key Theory

Question 15

Question
This is a quantitative study of the energy transformations in the living cell
Answer
  • Bioenergetics
  • Thermodynamics
  • Proteomics
  • Metabolomics

Question 16

Question
Which of the following hormones promotes rapid glycogenolysis in both liver and muscle
Answer
  • ACTH
  • Glutamine
  • Epinephrine
  • Prolactin

Question 17

Question
Which vitamin can be used in the management of hyperlipidemia?
Answer
  • Thiamine
  • Riboflavin
  • Niacin
  • Pantothenic acid

Question 18

Question
Bond between 2 amino acids
Answer
  • Glycosidic bond
  • N-glycosyl linkage
  • Peptide Bond
  • Hydrogen bond

Question 19

Question
Beta oxidation of fatty acids in eukaryotic cells occurs in the
Answer
  • Cytosol
  • Mitochondria
  • Endoplasmic reticulum
  • Ribosomes

Question 20

Question
The pentose phosphate pathway (aka HMP Shunt) occurs in the ________ of the liver, muscle and kidney.
Answer
  • cytosol
  • mitochondria
  • endoplasmic reticulum
  • ribosomes

Question 21

Question
The isoelectric point is the
Answer
  • pH where the alpha amino acid exist in its negatively charged form
  • pH wherein the amino acid exist in zwitterionic form
  • Temperature at which the amino acid denatures
  • Pressure at which the amino acid hydrolyzes

Question 22

Question
This is the only optically inactive amino acid
Answer
  • methionine
  • Lysine
  • Citrulline
  • glycine

Question 23

Question
This level of protein structure is applicable only to those have several subunits
Answer
  • Primary
  • Secondary
  • Tertiary
  • Quaternary

Question 24

Question
Arginine is the only metabolite of the urea cycle that does not accumulate because
Answer
  • It is readily excreted
  • It is used up by the body for protein synthesis
  • There is no known deficiency in the enzyme that catabolizes it
  • It can be acquired from food

Question 25

Question
This is the genetic condition characterized by deficiency of the enzyme branched chain alpha-keto acid dehydrogenase
Answer
  • Maple syrup disease
  • Hartnup disease
  • Kwashiorkor
  • Marasmus

Question 26

Question
These are compounds related to cerebrosides that contain sphingosine, long chain fatty acids, hexoses (usually galactose or glucose) and neuraminic acid
Answer
  • cephalins
  • gangliosides
  • cytolipins
  • lecithins

Question 27

Question
This enzyme catalyzes the conversion fructose-6-P to fructose-1,6-bis-P
Answer
  • hexokinase
  • pyruvate kinase
  • PFK-1
  • Fructose bisphosphatase

Question 28

Question
Which of the following is called transamination?
Answer
  • Conversion of amino acids to hydroxyl groups
  • Conversion of amino acids to keto acids
  • Loss of ammonia from amino acids
  • Formation of ammonium salts from ammonia

Question 29

Question
The sugar involved in the DNA
Answer
  • ribose
  • pentose
  • deoxyribose
  • xylose

Question 30

Question
This is the reason why blood AB is considered as the universal recipient.
Answer
  • It is the most common among the ABO blood types
  • Blood type AB has neither A nor B substances
  • Blood type AB has no anti-A or anti-B antibodies
  • All of the above

Question 31

Question
Which one is true regarding the structures of lipids?
Answer
  • Eicosapentaenoic acid is a saturated fatty acid
  • They may exist as esters of cholesterol when they are enclosed in very low density
  • Linoleic acid is an omega-3 fatty acid
  • Capric acid contains 12 carbons

Question 32

Question
This is the product of basic hydrolysis of fats and oils
Answer
  • fatty acid
  • triacylglycerol
  • soap
  • detergent

Question 33

Question
The group of lipids that is considered amphipathic
Answer
  • sterols
  • fatty acids
  • trans-fatty acids
  • phospholipids

Question 34

Question
Which properly describes a liposome?
Answer
  • It is a hollow sphere-like structure composed of a lipid bilayer enclosing an aqueous cavity
  • It is a lipid structure wherein the hydrophobic chains of the fatty acids are sequestered at the core of the sphere with virtually no water in the hydrophobic interior
  • It is a lipoprotein integrated in the phospholipid bilayer of the cell membranes
  • It is a hollow sphere-like structure composed of a lipid monolayer enclosing a hydrophobic cavity

Question 35

Question
It is the building block of essential fatty acids
Answer
  • Malonyl CoA
  • Phosphoribosyl pyrophosphate
  • Acetyl CoA
  • HMG CoA

Question 36

Question
The digestion of carbohydrates begins in the________.
Answer
  • mouth
  • stomach
  • small intestine
  • duodenum

Question 37

Question
Cellular elements of the blood devoid of nucleus
Answer
  • RBC
  • WBC
  • thrombocytes
  • all of the above

Question 38

Question
Conjugated proteins which are a combination of amino acids and carbohydrates
Answer
  • nucleoproteins
  • glycoproteins
  • phosphoproteins
  • chromoproteins

Question 39

Question
Glucose is normally absent in the urine because kidneys normally completely reabsorb all glucose. Which of the following is true?
Answer
  • Glucosuria confirms diabetes mellitus
  • Glucosuria necessarily means hyperglycemia
  • Glucosuria is solely attributed to insulin problem
  • Glucosuria may occur in other disease states

Question 40

Question
Wernicke-Korsakoff syndrome which can cause acute confusion, ataxia and ophthalmoplegia, can be treated with which of the following?
Answer
  • riboflavin
  • ascorbic acid
  • thiamine
  • pantothenic acid

Question 41

Question
This is the major excretory product of purine nucleotides
Answer
  • inosine monophosphate
  • uric acid
  • methylmalonyl CoA
  • tetrahydrofolate

Question 42

Question
This is the phenomena of renaturation of nucleic acid after it has been subjected to high temperature and then to room temperature
Answer
  • Hydrolysis
  • Polymerase chain reaction
  • annealing
  • hybridization

Question 43

Question
This is the base sequence for the start codon
Answer
  • UAG
  • UGA
  • AUG
  • UAA

Question 44

Question
This feature of bacterial cells confers selectivity of antibacterial agents targeting protein synthesis to the bacteria and not to the host cell.
Answer
  • mRNA
  • 40s ribosomal subunit
  • lack of cell wall
  • 30s ribosomal subunit

Question 45

Question
This is also known as the RNA-directed DNA polymerase
Answer
  • RNA polymerase II
  • Reverse transcriptase
  • DNA polymerase alpha
  • DNA polymerase II

Question 46

Question
What essential amino acid is used in the synthesis of niacin?
Answer
  • Tyrosine
  • Methionine
  • tryptophan
  • Phenylalanine

Question 47

Question
The cellular particles are often referred to by their sedimentation coefficient value, for example 70s ribosomes that are expressed in terms of 10 -13 seconds. The abbreviation “s” stands for
Answer
  • subunit
  • Seconds
  • Svedberg
  • None of the above

Question 48

Question
The best known building blocks of RNA and DNA are
Answer
  • purines
  • pyrimidines
  • fatty acids
  • a and b

Question 49

Question
The following are pathological constituents of urine, except:
Answer
  • glucose
  • albumin
  • creatinine
  • blood

Question 50

Question
Glucose and galactose differ only in the configuration of their hydroxyl group at carbon 4. Glucose and galactose are:
Answer
  • diastereomers
  • enantiomers
  • epimers
  • anomers

Question 51

Question
The chemical representation shows the most stable conformation of hexoaldopyranoses
Answer
  • Fischer projection
  • Boat conformation
  • Haworth Formula
  • Chair conformation

Question 52

Question
These are vegetables or animal drugs that consist of natural substances that have undergone only the process of collection and drying
Answer
  • natural substances
  • crude drugs
  • Extractives
  • Derivatives

Question 53

Question
What do you call plants growing in their native countries?
Answer
  • indigenous
  • naturalized
  • cultivated
  • local

Question 54

Question
What is used to treat cascara sagrada extract to reduce its bitter taste?
Answer
  • Magnesium oxide
  • Calcium carbonate
  • Simple syrup
  • Talc

Question 55

Question
What type of saponin glycosides are derivatives of steroids with spiroketal side chains?
Answer
  • Acid saponins
  • Alkaline saponins
  • Neutral saponins
  • None of the above

Question 56

Question
This is the final step in the preparation of drugs for the commercial market, consisting of the removal of extraneous matter.
Answer
  • Packaging
  • Preservation
  • Garbling
  • Harvesting

Question 57

Question
Natural relationship existing among plants and among animals
Answer
  • taxonomy
  • morphology
  • phylogeny
  • Systematics

Question 58

Question
8. In the preservation of crude drugs, this method is the simplest in preventing insect attacks and other form of destruction
Answer
  • Exposure of the drug to a temperature of 65°C
  • Use of methyl chloride
  • adding a few drops of benzene
  • AOTA

Question 59

Question
This refers to the evaluation by means of the sense organs and includes the macroscopic appearance of the drug, odor, taste, sound upon fracture and feel to the touch
Answer
  • Physical Analysis
  • Chemical Analysis
  • Proximate Analysis
  • Organoleptic Analysis

Question 60

Question
The first commercial application of the technique in pharmaco-biotechnology was made by Eli Lilly Company. Using the non-disease producing strain of E.coli, this company produced the hormone
Answer
  • Glucagon
  • somatostatin
  • insulin
  • somatomedin

Question 61

Question
Which of the following may influence the secondary constituents of plant drugs?
Answer
  • genetic composition
  • ontogeny
  • environment
  • all of the above

Question 62

Question
These are products of natural origin many of which without therapeutic effect used by the laity in the self-treatment of diseases.
Answer
  • Health Foods
  • Crude drugs
  • Extracts
  • AOTA

Question 63

Question
Which of the following statement/s is/are true? I. Gums and mucilages are carbohydrates II. Streptomycin is a carbohydrate III. The concentration of secondary metabolites increases with age IV. Biogenesis refers to the study of biochemical pathways leading to the formation of secondary constituents used as drugs
Answer
  • I, II and IV
  • I, II and III
  • I and III
  • III Only

Question 64

Question
Which of the following pairs is correct?
Answer
  • reserpine-hypotensive
  • sambong-stomachic
  • bayabas-diuretic
  • lagundi-analgesic

Question 65

Question
Which of the following statements is/are correct?
Answer
  • Synthetic Camphor is levorotatory
  • Natural Camphor is dextrorotatory
  • Both natural and semisynthetic camphor are racemic
  • NOTA

Question 66

Question
Give the proper sequence of the following processes in the preparation of natural drugs. I. Garbling II. Collection III. Drying IV. Harvesting V. Packaging
Answer
  • III-I-IV-II-V
  • II-IV-III-I-V
  • II-I-IV-V-III
  • IV-I-III-V-II

Question 67

Question
This classification of drugs considers the natural relationship or phylogeny among plants and animals.
Answer
  • taxonomic
  • morphologic
  • zoologic
  • zoologic and taxonomic

Question 68

Question
The source of bassorin
Answer
  • acacia
  • Karaya
  • gum
  • Tragacanth

Question 69

Question
Mannitol is used pharmacologically as a/an
Answer
  • humectant
  • osmotic diuretic
  • anti-infective
  • urologic irritant

Question 70

Question
Which of the following is/are homoglycan(s)?
Answer
  • starch
  • starch and inulin
  • inulin
  • gums

Question 71

Question
The milk left after separation of the cream
Answer
  • cheese
  • condensed milk
  • skimmed milk
  • buttermilk

Question 72

Question
Fermentation product from molasses
Answer
  • wine
  • whiskey
  • rum
  • brandy

Question 73

Question
It is also known as the carob pulp or St. John's Bread
Answer
  • locust bean
  • Xanthan
  • guar
  • acacia

Question 74

Question
It tastes approximately half as sweet as sucrose, and has humectant properties which makes it a useful ingredient in toothpastes, chewing gums, and dietetic products.
Answer
  • mannitol
  • fructose
  • dulcitol
  • sorbitol

Question 75

Question
A pharmaceutical aid in the preparation of collodion and flexible collodion.
Answer
  • methylcellulose phthalate
  • soluble guncotton
  • powdered cellulose
  • cellulose acetate

Question 76

Question
Gum usually used as a substitute for acacia
Answer
  • ghatti
  • tragacanth
  • karaya
  • algin

Question 77

Question
It is also referred to as Japanese Isinglass, and is extensively used as a gel in bacteriologic culture media.
Answer
  • carrageenan
  • agar
  • chondrus
  • cydonium

Question 78

Question
Powdered cellulose is the purified, mechanically disintegrated cellulose used as a self-binding tablet diluent and disintegrating agent. Which of the following statements regarding powdered cellulose is correct? A) The purity of cellulose is defined by its solubility in hydrochloric acid. B) The cellulose remaining insoluble is termed a-cellulose. C) The greater the quantity of a-cellulose present, the higher the quality of the material.
Answer
  • B and C only
  • A and B only
  • B only
  • NOTA

Question 79

Question
The most important monosaccharides found in plants
Answer
  • hexoses
  • pentoses
  • heptoses
  • octoses

Question 80

Question
Which of the following is a source of sucrose?
Answer
  • Acer saccharum
  • Bos taurus
  • Prunus cerasus
  • Sorbus aucuparia

Question 81

Question
Which of the following statements is/are true?
Answer
  • Dextrose is a-(L)-glucopyranose
  • Dextrose is obtained from controlled enzymatic hydrolysis of starch
  • Dextrose can only be given PO and IV
  • AOTA

Question 82

Question
This is a product obtained from the incomplete hydrolysis of starch. It is a colorless or yellowish, thick syrupy liquid that is nearly odorless and tastes sweet.
Answer
  • liquid dextrose
  • liquid sucrose
  • liquid dextrin
  • liquid glucose

Question 83

Question
Which of the following pairs is correct?
Answer
  • Ferrous gluconate - hematinic
  • Xylose-laxative
  • Lactulose-diagnostic aid
  • AOTA

Question 84

Question
Which of the following statements refers to fructose? A) from honey B) obtained from the inversion of aqueous solutions of sucrose C) upon hydrolysis, sucrose yields a higher fructose than dextrose content
Answer
  • A and B only
  • B and C only
  • C only
  • B only

Question 85

Question
In milk processing, the liquid separated from coagulum is known as
Answer
  • condensed milk
  • butter
  • buttermilk
  • whey

Question 86

Question
This is a pentose also known as wood sugar, which is obtained by boiling corn cobs, straw, or similar materials with dilute acid to hydrolyze the polymer.
Answer
  • ribose
  • xylose
  • erythrose
  • trehalose

Question 87

Question
Which of the following statements concerning lactulose is true?
Answer
  • Natural sugar prepared by acidic rearrangement of lactose
  • Trisaccharide
  • Well absorbed
  • Bacteria in the colon metabolize it to acetic acid and lactic acid

Question 88

Question
Xylose is used as a /an
Answer
  • diuretic
  • pharmaceutical excipient
  • binder
  • diagnostic aid

Question 89

Question
In glycolysis, what enzyme is involved in the conversion of 3 phosphoglyceraldehyde to 1,3-Bisphosphoglyceric acid?
Answer
  • kinase
  • aldolase
  • dehydrogenase
  • isomerase

Question 90

Question
Aside from thiamine pyrophosphate, what coenzyme/cofactor aids in the oxidative decarboxylation of pyruvic acid with pyruvic acid dehydrogenase?
Answer
  • NAD
  • Lipoic Acid
  • FAD
  • Mg

Question 91

Question
Glucose-6-PO, is converted to ____ upon the action of phosphohexose isomerase.
Answer
  • Glucose-1-Phosphate
  • Fructose-6-Phosphate
  • Fructose-1.6-Diphosphate
  • Dihydroxyacetone phosphate

Question 92

Question
Pyruvic acid, upon the action of pyruvic acid decarboxylase yields ____
Answer
  • ethanol
  • lactic acid
  • methanol
  • acetaldehyde

Question 93

Question
Alcohol dehydrogenase acts on acetaldehyde to yield ____
Answer
  • lactic acid
  • pyruvic acid
  • ethanol
  • AOTA

Question 94

Question
Which tricarboxylic acid was first isolated by scheele in 1784
Answer
  • citric acid
  • Tartaric acid
  • lactic acid
  • fumaric acid

Question 95

Question
This acid is a byproduct of wine
Answer
  • citric acid
  • tartaric acid
  • lactic acid
  • fumaric acid

Question 96

Question
This acid used as an acidulant especially in feeding formulas
Answer
  • Citric acid
  • tartaric acid
  • lactic acid
  • fumaric acid

Question 97

Question
Which of the following may be produced from the process of distillation?
Answer
  • whiskey
  • rum
  • brandy
  • AOTA

Question 98

Question
Which of the following statement/s is/are true?
Answer
  • Wine is sometimes used medically as a mild stimulant and tonic
  • Brandy is used as CNS stimulant
  • Whiskey is used as CNS stimulant
  • AOTA

Question 99

Question
Which of the following is obtained from Fraxinus ornus I. (Fam. Oleaceae), and is used for its laxative properties?
Answer
  • glucitol
  • mannitol
  • Sorbitol
  • Lactose

Question 100

Question
What is the usual diagnostic dose of mannitol injection?
Answer
  • 200 mg/kg body weight in a 15-25% solution IV in 3-5 minutes
  • 50-100g daily in a 5-25% solution by IV infusion
  • 200 g/kg body weight in a 15-25% solution in 3-5 minutes
  • 50-100 kg daily in a 5-25% solution by IV infusion
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