5014830
Question 1
Question
The three vesicle stage occurs at the 3rd week of gestation. The five vesicle stage occurs at the 5th week of gestation
Answer
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both true
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first true second false
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first false second true
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both false
Question 2
Question
The Prechodal plate produces FGF to regulate midline structure development of the brain and face. The Anterior Neural Ridge produces SHH to regulate development of the telencephalon.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both statements false
Question 3
Question
The prechodal plate is derived from?
Answer
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Ectoderm
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Mesoderm
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Endoderm
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Dermis
Question 4
Question
The isthmus is between the forebrain and midbrain and regulates their development. It produces both FGF and WNT.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both false
Question 5
Question
Some neurons from the corpus striatum gives rise to part of the cerebral cortex. Most of the cerebral cortex comes from the pallium.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both false
Question 6
Question
Which of the following is a vertebral fusion defect where both the neural tissue and meninges protrude?
Answer
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spina bifida occulta
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meningocele
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meningomyelocele
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myeloschisis
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Arnold-Chiari malformation
Question 7
Question
Which of the following is incorrectly matched?
Answer
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Spina Bifida occulta: the bony defect is covered by skin, intact spinal cord
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Spina Bifida Cystica: there is a protrusion of meninges and neural tissue (meningomyelocele)
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Meningocele: only the meninges protrude
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Anencephaly- open brain
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Craniorachischisis: neural tube defect at the brain and spinal cord
Question 8
Question
In normal development, the spinal cord elongates faster than the vertebral column. In Spina Bifida Cystica, as the vertebral column elongates, the force stretches the spinal cord which causes the herniation of the cerebellum.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both false
Question 9
Question
The bone most frequently affected by neural tube defects is the occipital bone. Small defects can cause meningoencephalocele.
Answer
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Both true
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First true, second false
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First false, second true
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Both false
Question 10
Question
Meningoencephalocele is protrusion of just the brain tissue and meninges. Meningohydroencephalocele involves protrusion of the meninges, brain tissue and ventricle.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both statements false
Question 11
Question
Which of the following is correct?
Answer
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Lobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects
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Alobar HPE- one telencephalic vesicle, one eye, one nasal chamber, other midline defects
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Smith-Lemli-Opitz involves EMX 2, is autosomal recessive, assorted defects of face, heart, brain, limbs
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Schizencephaly- involves DHCR 7, causes large clefts in cerebral hemispheres
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Microcephaly- caused by smaller cranial vault leading to less brain development
Question 12
Question
Hydrocephaly is often due to a blockage in the lateral and third ventricles. The accumulated fluid leads to thinner bones of skull and cerebral cortex and an enlarged head.
Answer
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Both statements true
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First true, second false
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First false, second true
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Both false.
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