The energy we use
for muscle
contractions comes
from adenosine
triphosphate (ATP)
The energy that is stored in ATP is released by
breaking down bonds. Enzymes are used to
break down the compound, ATP-ase is used
leaving ADP and Pi
The Body constantly rebuild ATP by
converting ADP and Pi back into ATP.
We re-synthesise ATP through three
different types of chemical reaction in the
muscle cell; Fuelled by either food, or a
chemical called phosphocreatine. Or finally
the conversion of theses fuels through one
of the three energy systems
Aerobic
System
Used when
intensity of
exercise is low
and oxygen
supply is high
e.g. long
distance
running
Stage 1; Glycolysis
Takes place
in the
sarcoplasm
of the
muscle
It is the break
down of
glucose into
pyruvic acid
For every molecule
of glucose
undergoing
glycolysis, a net of
two molecules of
ATP are produced.
Before the pyruvic acid produced can
enter the next stage, it splits into two
acetyl groups and is the carried into
the kerb cycle by coenzyme A
Stage 2: The kerb cycle
Acetyl coenzyme A
combines with
oxaloacetic acid,
forming citric acid.
Hydrogen is removed from citric
acid and the rearranged form of
citric acid undergoes 'oxidative
carboxylation'. (hydrogen is given
off)
The carbon forms CO2, which is
transported to the lungs and
breathed out and the hydrogen is
taken to the electron transport
chain
Fats can enter the Kerb cycle.
Stored fats are
broken down into
glycerol and free
fatty acids for
transportation in
the blood
These fatty acids
under go 'Beta
oxidation'
Beta oxidation: A
process where fatty
acids are broken down
to generate acetyl-
Coenzyme A which
enters the kerb cycle.
2 ATP
molecules
are
produced
Stage 3: Electron Transport Chain
Hydrogen is
transported into
the ETC by
hydrogen carriers.
This occurs in
the cristae of
the
mitochondria
The hydrogen splits
into hydrogen ions
and electrons and
they are charged
with potential
energy
The hydrogen ions are
oxidised to form water,
while the hydrogen
electrons provide the
energy needed to
re-synthesis ATP
34
Molecules
of ATP are
produced
ATP-PC system
Uses phosphocreatine (PC)
as fuel. It can be broken
down quickly and easily to
release energy to
re-synthesise ATP
Anaerobic Process
It re-synthesises ATP when the
enzyme creatine kinase
detects high levels of ADP
It breaks down PC in the
muscles into phosphate (pi)
and creatine (c), releasing
energy
PC---> Pi + C + energy
The energy is then used to
convert ADP to ATP in a
coupled reaction
Energy ---> Pi + ADP ----> ATP
Short term lactate anaerobic system
Provides energy for
high-intensity exercise,
longer than the
ATP-PC system
How long the system
lasts depends on the
fitness of the
individual
When the PC stores are low, the
enzyme glycogen phosphorylase is
activated to break down glycogen
into glucose, which is further broken
down into pyruvic acid by the
enzyme phosphofructokinase