8956344
Description
Mind Map by rania khalil, updated more than 1 year ago
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Created by rania khalil
over 7 years ago
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Sana With Rash & Bruising
- thrombopoiesis
- Process by which mature platelets are generated within the bone marrow
- Process by which mature platelets are generated within the bone marrow
- Hemostasis
- blood coagulation mechanism
- causes
- causes
- bleeding disorders
- history taking
- investigations
- causes
- platelets
- qualitative
- quantitative
- Thrombocytopenia
- Idiopathic thrombocytopenic purpura
- lead to easy or excessive bruising and bleeding. The
bleeding results from unusually low levels of platelets
- Acute ITP: less than 6 months usually
presents as a childhood
- Chronic ITP 6 months or longer occurs most
commonly between the ages of 20 and 50 years
- secondary if it is
associated with an
underlying disorder;
autoimmune
disorders, particularly
systemic lupus
erythematosus (SLE),
and infections, such
as HIV and hepatitis C
- secondary if it is
associated with an
underlying disorder;
autoimmune
disorders, particularly
systemic lupus
erythematosus (SLE),
and infections, such
as HIV and hepatitis C
- Chronic ITP 6 months or longer occurs most
commonly between the ages of 20 and 50 years
- Risk FactorsGenetics Gender Age
Receiving certain vaccines. Although very
rare, some vaccinations can “trigger” ITP.
Viral infections
- The signs of bleeding
include: Petechiae (<
3mm) Purpura (3-10 mm)
Ecchymoses (> 1 cm)
Hematoma Nosebleeds or
bleeding from the gums
Blood in urine or stool
- The signs of bleeding
include: Petechiae (<
3mm) Purpura (3-10 mm)
Ecchymoses (> 1 cm)
Hematoma Nosebleeds or
bleeding from the gums
Blood in urine or stool
- Acute ITP: less than 6 months usually
presents as a childhood
- treatment
- spleen
- spleen
- lead to easy or excessive bruising and bleeding. The
bleeding results from unusually low levels of platelets
- Decreased production: Aplastic aneamia-
megaloblastic anemia-drugs- infections (HIV),
leukemia
- Decreased survival: immune thrombocytopenic
purpura (ITP)-drug induced (heparin-
quinidine)-Dissiminated intravascular coagulopathy
(DIC)- thrombotic thrombocytopenic purpura (TTP)
- Idiopathic thrombocytopenic purpura
- Thrombocytopenia
- qualitative
- Coagulation
factors
- types
- types
- Vessel
Wall
- Congenital defects of the vessel wall
- Senile purpura:
- Scurvy
- Septic Vasculitis
- Congenital defects of the vessel wall
- platelets
- history taking
- defect leads to
- blood coagulation mechanism
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