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8266368
Classification of the Immune System
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Classification of the Immune System
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Alma Cariño
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Classification of the Immune System
Adaptative immune system
Humoral immunity
Mediated by B-cells
Matures in the bone marrow
Plasma cells
Secretes antibodies
Memory B-cells
Produce plasma cells that directly secrete IgG antibodies in second exposure to antigen
Cellular immunity
Mediated by T-cells
Active other immune cells to fully mature
CD8+cytotoxic T-cells
Induce apoptosis in target cells
CD4+ helped T-cells
Th1
Activate macrophages to destroy pathogens
B-cell activation roles
Th2
Interacts with B-cells mainly
Th17
Fight fungal infections
Innate Immune System
Response to an initial infection
Immediate: 0-4 hours
Infection
Recognition by preformed, nonspecific and broadly specific effectors
Removal of Infectious agent
Consists of Cells and Proteins
Main components
Physical epithelial barriers
Phagocytic leukocytes
Dendritic cells
Special type ok lymphocyte - Natural Killer cell (NK)
Circulating plasma proteins
Active Immune System
Injection a person with
Antigens
Source of antibodies
The person inoculated
Method
Injection with
Attenuated pathogens
Their toxins
Time to develop resistance
5 to 14 days
Duration of resistance
Long (Perhaps years)
When used
Before Exposure to pathogen
Passive Immune System
Adquiere from the transfer of antibodies
Produce by other person
protection decreases in a short time
Weeks or months
Acquired Immunity
Naturally
Antibodies pass from mother to fetus
Via placenta
To infant in her milk
Artificially
Injection of immune serum
Gamma globulin
Anexos de mídia
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