Questão 1
Questão
How many ATPs go where?
(btw, "1 ATP" goes before "1ATP")
Responda
-
2 ATP
-
2ATP
-
ATP
-
4 ATP
-
36 ATP
-
129 ATP
Questão 2
Questão
Free fatty acids (NEFA / Non-Esterified Fatty Acids) vs TriAcylGlycerides (/TAGs).
[blank_start]__________[blank_end] circulate bound to albumin.
[blank_start]__________[blank_end] circulate within [blank_start]__________[blank_end] released from the liver or [blank_start]__________[blank_end] released from the gut.
Responda
-
NEFA
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TAGs
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VLDLs
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Chylomicrons
Questão 3
Questão
Lipid uptake.
Put the three in order (they’re written alphabetically here)
[blank_start]__________[blank_end] Cholesterol-rich LDL interact with LDL-R and scavenger receptors; enters lysosomal pathway for hydrolysis;
[blank_start]__________[blank_end] Hepatic Lipase and Lipoprotein Lipase reside on endothelial cells to hydrolyse VLDL and Chylomicron TAG to FFAs for uptake;
[blank_start]__________[blank_end] TAG-rich VLDL interact with VLDL-R, enters lysosomal pathway where acid lipases hydrolyse TAG.
Questão 4
Questão
Familial Lipoprotein Lipase Deficiency is:
Responda
-
Autosomal DOMINANT
-
Autosomal RECESSIVE
Questão 5
Questão
LPL deficiency causes [blank_start]__________[blank_end], which leads to [blank_start]__________[blank_end].
Questão 6
Questão
Fatty Acid Metabolism has two major pathways: TriAcylGlycerol metabolism and β-Oxidation.
FA uptake is a 2-step process. In which order does it happen?
Questão 7
Responda
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Consumes 1 ATP
-
Is irreversible
-
Is reversible
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Consumes 2 ATP
-
Consumes 4 ATP
-
Consumes 36 ATP
Questão 8
Questão
De Novo Fatty Acid Synthesis uses [blank_start]__________[blank_end] (from Glucose and Amino acids) to generate [blank_start]__________[blank_end] as the starting substrate to firstly produce [blank_start]__________[blank_end] (C16:O).
Responda
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Citrate
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Acetyl-CoA
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Malonyl-CoA
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Palmitate
Questão 9
Questão
De Novo Fatty Acid Synthesis uses up how many ATP molecules?
Questão 10
Questão
CPT1 turns Carnitine into FA-Carnitine, allowing it to be uptaken into a cell. This can be blocked by which of the following?
Questão 11
Questão
MCD deficiency (and some similar disorders) prevent [blank_start]__________[blank_end] from being turned into [blank_start]__________[blank_end]. This results in [blank_start]__________[blank_end] of CPT1 (and thus [blank_start]__________[blank_end] FA uptake).
Responda
-
Malonyl-CoA
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Acetyl-CoA
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Blockage
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Stimulation
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Reduces
-
Increases
Questão 12
Questão
What goes where?
(within each box, put the two in alphabetical order)
Responda
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Adipose-derived Fatty Acids
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Chylomicron-derived Fatty Acids
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De novo Lipogenesis
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Re-esterification
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Fatty Acid Oxidation
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TAG Secretion (e.g. VLDL)