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13553577
Clinical biochemistry
Description
Liver disease test
No tags specified
clinical biochemistry
Quiz by
Thomas Hardwick
, updated more than 1 year ago
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Created by
Thomas Hardwick
over 6 years ago
615
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Resource summary
Question 1
Question
Which of the following is an inherited disorder of bilirubin metabolism?
Answer
All answers are correct
Crigler-Najjar syndrome
Gilbert’s disease
Dubin-Johnson syndrome
Question 2
Question
Which of the following enzymes would be raised in serum from a patient with hepatocellular disease?
Answer
Creatine kinase
Lactate dehydrogenase
Alanine amino transerferase
Ferroxidase
Question 3
Question
Which of the following is the major liver metabolite of bilirubin
Answer
stercobilin
bilirubin monoglucuronide
unconjugated bilirubin bilirubin diglucuronide
bilirubin diglucuronide
Question 4
Question
Which of the following does not cause chronic liver disease?
Answer
Hepatitis A
Hepatitis C
Chronic high alcohol ingestion
Hepatitis B
none of them
Question 5
Question
Which of the following best defines jaundice?
Answer
Yellow discolouration of the skin or sclera of the eye, due to increased bilirubin in plasma >40umol/l Low serum bilirubin concentration
Increased bilirubin in plasma >40umol/l
Brain damage due to high bilirubin concentrations
Low serum bilirubin concentration
Question 6
Question
Which of the following can arise as a result of acute hepatic failure?
Answer
Acid-base disturbance
Hypoglycaemia
Electrolyte imbalance
All answers are correct
Question 7
Question
Which of the following can be a cause of acute liver disease?
Answer
Heart failure leading to inadequate liver perfusion
Paracetamol poisoning
All answers are correct
Hepatitis B
Question 8
Question
Which is found in haemolytic jaundice?
Answer
Increased serum haptoglobins
Low serum unconjugated bilirubin
Pale stools due to decreased bilirubin metabolites
High serum unconjugated bilirubin
Question 9
Question
Which of the following can cause liver cirrhosis?
Answer
All answers are correct
Chronic high alcohol ingestion
Chronic hepatitis B infection
Anti-mitochondrial antibodies
Question 10
Question
Which is found in obstructive jaundice?
Answer
High serum unconjugated bilirubin
High serum conjugated bilirubin
Dark stools due to increased bilirubin metabolites
Increased serum haptoglobin
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