Zusammenfassung der Ressource
Frage 1
Frage
Autocrine vs paracrine vs endocrine signalling:
Autocrine = Acts on [blank_start]__________[blank_end];
Endocrine = Acts on [blank_start]__________[blank_end];
Paracrine = Acts on[blank_start]__________[blank_end];
Antworten
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Itself
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Distant tissue
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Nearby tissue
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External organisms
Frage 2
Antworten
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RANKL
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RANK
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OPG
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CSF-1
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Calcitonin
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PTH
Frage 3
Frage
What does OPG do to RANKL?
Frage 4
Frage
What effect does Calcitonin have on Osteoblasts?
Frage 5
Frage
What effect does Calcitonin have on Osteoclasts?
Frage 6
Frage
What effect does CSF1 have on Osteoblasts?
Frage 7
Frage
What effect does CSF1 have on Osteoclasts?
Frage 8
Frage
OCN is a hormone involved in the regulation of glucose metabolism, which improves the sensitivity of target organs to insulin, thus improving glucose handling by the body. …and MAYBE stimulates insulin production/secretion. Still, OCN = ??
Antworten
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OsteoCalciN
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OsteoCalcitoniN
Frage 9
Frage
OCN is the most abundant [blank_start]__________[blank_end] in bone.
Antworten
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Non-collagenous protein
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Mineral
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Collagenous protein
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Neurotransmitter
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Osteokine
Frage 10
Antworten
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Autosomal Dominant Hypophosphataemic Rickets
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Adrenal Dominant Hypophosphataemic Rickets
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Autosomal Dominant Hyperphosphataemic Rickets
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Adrenal Dominant Hyperphosphataemic Rickets
Frage 11
Antworten
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Oncogenic OsteoMalacia
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Osteogenic OncoMalacia
Frage 12
Frage
ADHR and OOM are examples of what?
Antworten
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Phosphate-wasting disorders
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Calcium-wasting disorders
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Vitamin-D-wasting disorders
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Vitamin-K-wasting disorders
Frage 13
Frage
Mis-sense mutations in [blank_start]__________[blank_end] in ADHR patients at a furin consensus cleavage site results in a resistance to proteolysis.
Antworten
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FGF23
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Interleukin 6
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Interleukin 15
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FGF6
Frage 14
Frage
FGF23 regulates [blank_start]__________[blank_end] concentrations in plasma. It’s secreted by osteocytes in response to low [above] or [blank_start]__________[blank_end] Vitamin D.
Antworten
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Phosphate
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OPG
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OCN
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Calcium
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Vitamin D
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High
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Low
Frage 15
Frage
FGF23 acts on the kidneys, where it [blank_start]__________[blank_end] the expression of NPT2 (a Na-PO4 co-transporter in the proximal tubule). This leads to [blank_start]__________[blank_end] PO4 reabsorption (which results in [blank_start]__________[blank_end] excretion).
Antworten
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Decreases
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Increases
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Increased
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Decreased
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Increased
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Decreased