BMS09-1014 - Bone Development and Ossification

Descripción

main types of cartilage/location. characteristics of main types of cartilage. method of growth of cartilage vs. bone. Where cartilage can be replaced by bone. origin/lineage of cells found in bone. processes of intramembranous/endochondral ossification+sequence of bone formation location and the differences of primary/ secondary ossification centres+primary/secondary spongiosa structure, characteristics, function of epiphyseal growth plate appositional vs.. interstitial
Evian Chai
Fichas por Evian Chai, actualizado hace más de 1 año
Evian Chai
Creado por Evian Chai hace más de 4 años
1633
0

Resumen del Recurso

Pregunta Respuesta
What is the difference between appositional and interstitial growth? Appositional is matrix deposition ON existing matrix, growth in length Interstitial is matrix deposition from WITHIN matrix, growth in width
Appositional growth occurs in Bone and cartilage
Interstitial growth occurs in Only cartilage (bone too rigid)
What is intramembranous ossification? Direct bone formation from osteoprogenitors
What are the steps of intramembranous ossification? 1. Formation of periosteum 2. Differentiation to osteoblasts 3. Matrix deposition 4. Mineralisation 5. Vascularisation, blood vessels 6. Growth/remodelling
What is the periosteum and its two layers? A dense fibrous layer lining bone Outer fibrous layer and inner cambium layer
What is in the outer fibrous layer of the periosteum? Collagen/nerve fibers/blood supply
What is in the inner cambium layer of the periosteum? Osteoblasts
Label the five zones of the epiphyseal growth plate 1. Resting zone 2. Proliferation zone - chrondoblasts divide quickly 3. Hypertrophic zone - chrondocytes enlarge, initiate calcification 4. Calcification zone - matrix calcifies, chrondocytes die 5. Ossification zone - osteoclasts digest calcified tissue, osteoblasts replace with bone
What zone do chrondocytes die in? Calcification zone
The epiphyseal growth plate ends before the ... zone Ossification zone (in metaphysis)
What is the primary spongiosa? Where is the primary spongiosa located? Bars of cartilage for bone to be built on Under the growth plate (metaphysis)
What type of bone is first made in the primary spongiosa? What is it replaced by? First woven (primary) bone Then remodelled into lamellar (secondary) bone
Where is the secondary spongiosa? How is it different from the primary? Right under the primary spongiosa Less cartilage, more new bone More organised, parallel rings of collagen Later becomes trabecular or cortical (compact) bone
What is the process of endochondral ossification? 1. PeriCHONdrium (cartilage) develops 2. Periostuem forms bony collar around diaphysis 2a. This becomes the primary ossification centre 3. Secondary ossification center develops at epiphysis 4. Growth plate develops between epiphysis/metaphysis
Where is the primary ossification center? What happens here? Diaphysis Capillaries invade periostuem, osteoclasts migrate and invade
Where is the secondary ossification center? At the epiphysis
Where does the epiphyseal growth plate develop? Between the metaphysis and the epiphysis
Label the Bone Top is Epiphysis Middle is Metaphysis Then diaphysis Metaphysis Epiphysis
What are the three types of cartilage? 1. Hyaline - Type II collagen fibers - Periosteum - Weakest of three 2. Fibro - alternating strips of hyaline cartilage and thick collagen strips - no perichondrium - strongest 3. Elastic - threadlike network of elastic fibers - perichondrium
Where is hyaline cartilage usually found? ribs, nose, larynx, trachea
Where is fibrocartilage usually found? Transition between hyaline cartilage and tendon/ligament invertebral discs, joint capsules, ligaments
Where is elastic cartilage usually found? external ear, epiglottis and larynx
Mostrar resumen completo Ocultar resumen completo

Similar

BMS09-1015 -Bone Cells, Cartilage and Function
Evian Chai
BMS09-1013 - Bones & Joints
Evian Chai
BMS10-1017 - Blood Cells: RBC WBC and platelets
Evian Chai
BMS03-1016 Organisation of the Nervous System)
Evian Chai
BMS11-1039 - Pharmacology of diuretics
Evian Chai
BMS07-1026- Glucose and Glycogen metabolism
Evian Chai
BMS03-1022- A pharmacological perspective of the autonomic nervous system
Evian Chai
BMS09-1016 -Bone Growth, Modelling and Remodelling
Evian Chai
BMS14-1062 - Histology of endocrine glands
Evian Chai
BMS03-1013- Cell Signalling 2
Evian Chai
BMS10-1027 (Control of Vasculature and Blood Pressure)
Evian Chai